Idiopathic membranoproliferative glomerulonephritis treated with mycophenolate mofetil

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Treatment of idiopathic membranoproliferative glomerulonephritis with mycophenolate mofetil and steroids.

BACKGROUND Treatment of adults with idiopathic membranoproliferative glomerulonephritis (IMPGN) is often unrewarding with approximately 60% of patients progressing to end-stage renal failure within 10 years. Although children with IMPGN may respond to steroid therapy, there is no significant benefit to treating adult IMPGN patients with immunosuppression. METHODS Outcome measures in five pati...

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Mycophenolate mofetil as a possible therapeutic option for idiopathic membranoproliferative glomerulonephritis

Sir, The high mortality rate associated with hip fracture in the general population, as well as in the end-stage renal disease (ESRD) population, is well described. However, the mortality associated with pelvis and lower limb fractures in ESRD patients remains unknown. We reviewed the medical records of all chronic haemodialysis or peritoneal dialysis patients hospitalized at Maisonneuve-Rosemo...

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Chapter 8: Idiopathic membranoproliferative glomerulonephritis

BACKGROUND MPGN is a light-microscopic ‘‘pattern of injury’’ caused by many disorders (see Table 20). Patients commonly present with nephrotic syndrome, hypertension, glomerular hematuria, and progressive kidney dysfunction. Reduction in the serum concentration of complement components (C3 and/or C4) is commonly, but not uniformly, observed. MPGN can be further classified based on the extent an...

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Infundibuloneurohypophysitis Associated With Sjögren Syndrome Successfully Treated With Mycophenolate Mofetil

Hypophysitis is an inflammatory disorder of the pituitary gland and corticosteroids are usually recommended as the first-line treatment. Hypophysitis related to primary Sjögren syndrome (pSS) is uncommon. We describe the unusual case of a patient with infundibuloneurohypophysitis associated with pSS successfully treated with mycophenolate mofetil (MMF).We describe a case of a 60-year-old man wi...

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Severe Relapsing Goodpasture's Disease Successfully Treated with Mycophenolate Mofetil

Goodpasture's disease is a rare autoimmune disorder characterised by the development of antiglomerular basement membrane autoantibodies, which typically presents with rapidly progressive crescentic glomerulonephritis and pulmonary haemorrhage. Even with aggressive nonspecific immunosuppression and plasma exchange, mortality remains high. We report a case of life-threatening Goodpasture's diseas...

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ژورنال

عنوان ژورنال: Clinical Case Reports

سال: 2018

ISSN: 2050-0904

DOI: 10.1002/ccr3.1826